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GB112544 Anti -PI 3 Kinase Catalytic Subunit Alpha PIK3CA Rabbit Polyclonal Antibody for IHC

Immunogen: KLH conjugated Synthetic peptide corresponding to Human PIK3CA
Isotype: IgG
Purity: Affinity purification
ul:
  • GB112544
  • Servicebio

Description

Product Information


Description

PI 3 Kinase catalytic subunit alpha/PIK3CA rabbit polyclonal

Protein full name

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Synonyms

PI3-kinase subunit alpha, PI3K-alpha, PtdIns-3-kinase subunit alpha, p110alpha, PIK3CA, PtdIns-3-kinase subunit p110-alpha

Immunogen

KLH conjugated Synthetic peptide

corresponding to Human PIK3CA

Isotype

IgG

Purity

Affinity purification

Predicted MW.

124 kDa

Observed MW.

110 kDa

Uniprot ID

P42336, P42337, A0A0G2K344




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Human, Mouse, Rat

1: 500-1: 1000

brain, hippocampus




Background


PIK3CA belongs to the PI3/PI4-kinase family. It phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2. Defects in PIK3CA are associated with colorectal cancer (CRC). Defects in PIK3CA are associated with breast cancer. Defects in PIK3CA are associated with ovarian cancer. Defects in PIK3CA may underlie hepatocellular carcinoma (HCC). Defects in PIK3CA are a cause of keratosis seborrheic (KERSEB).




Images


图片 1.png

Western blot analysis of PIK3CA (GB112544) 

at dilution of 1: 1000

Lane 1: HeLa cell lysate

Lane 2: Jurkat cell lysate

Lane 3: MCF7 cell lysate

Lane 4: RAW264.7 cell lysate

Lane 5: NIH3T3 cell lysate

Lane 6: Mouse brain tissue lysate

Lane 7: Mouse hippocampus tissue lysate

Lane 8: Rat brain tissue lysate

Lane 9: Rat hippocampus tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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