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GB112513 Anti -DCC CRCR1 CRC18 Netrin receptor DCC Rabbit Polyclonal Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse DCC
Isotype: IgG
Purity: Affinity purification
ul:
  • GB112513
  • Servicebio

Description

Product Information

 

Description

DCC rabbit polyclonal

Protein full name

Netrin receptor DCC

Synonyms

Tumor suppressor protein DCC, Dcc, CRCR1, CRC18, Colorectal cancer suppressor, Netrin receptor DCC

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse DCC

Isotype

IgG

Purity

Affinity purification

Predicted MW.

158 kDa

Observed MW.

158 kDa

Uniprot ID

P43146

 


 

Applications

 

Applications

Species

Dilution

Positive Tissue

WB

Human

1: 250-1: 500

U266

 


 

Background

 

The DCC protein is a type I transmembrane glycoprotein that belongs to the immunoglobulin (Ig) superfamily. The extracellular domain is composed of four Ig like domains and six fibronectin type III repeats. Native DCC is found in three isoforms. Two forms, a long and a short isoform, are produced from the same gene but have different initiation sites. The third isoform, produced by alternative splicing, is expressed only in embryonic tissue. Mouse DCC extracellular domain shares 97% and 99% homology with human and rat DCC extracellular domains, respectively. In adults, DCC is highly expressed in the brain but is also expressed at very low levels in multiple normal tissues. In the embyro, high levels of expression are detected in the brain and neural tube.

 


 

Images

 

图片 1.png

Western blot analysis of DCC (GB112513) 

at dilution of 1: 500

Lane 1: U266 cell lysate

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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