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GB112509 Anti -PDHA1 PDHCE1A Rabbit Polyclonal Antibody for WB

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse PDHA1
Isotype: IgG
Purity: Affinity purification
ul:
  • GB112509
  • Servicebio

Description

Product Information

 

Description

PDHA1 rabbit polyclonal

Protein full name

Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

Synonyms

PDHE1-A type I, Pdha1, Pdha-1, PHE1A, PDHCE1A

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse PDHA1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

43 kDa

Observed MW.

43 kDa

Uniprot ID

P35486, P26284

 


 

Applications

 

Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 350-1: 700

heart, liver, brain, kidney

 


 

Background

 

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase(E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. 

 


 

Images

 

 

Western blot analysis of PDHA1 (GB112509) 

at dilution of 1: 700

Lane 1: Mouse brain tissue lysate

Lane 2: Mouse liver tissue lysate

Lane 3: Mouse kidney tissue lysate

Lane 4: Rat brain tissue lysate

Lane 5: Rat liver tissue lysate

Lane 6: Rat kidney tissue lysate

Western blot analysis of PDHA1 (GB112509) 

at dilution of 1: 700

Lane 1: Mouse heart tissue lysate

Lane 2: Mouse liver tissue lysate

Lane 3: Mouse brain tissue lysate

Lane 4: Mouse kidney tissue lysate

Lane 5: Rat heart tissue lysate

Lane 6: Rat liver tissue lysate

Lane 7: Rat kidney tissue lysate

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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