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GB112486 Anti -ANGPTL3 ANG5 FHBL2 ANL3 Rabbit Polyclonal Antibody for WB

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse ANGPTL3
Isotype: IgG
Purity: Affinity purification
ul:
  • GB112486
  • Servicebio

Description

Product Information

 

Description

ANGPTL3 rabbit polyclonal

Protein full name

Angiopoietin-related protein 3

Synonyms

Angiopoietin-like protein 3, Angptl3, ANG5, Angiopoietin 5, Angiopoietin like 3, FHBL2, ANL3

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse ANGPTL3

Isotype

IgG

Purity

Affinity purification

Predicted MW.

53 kDa

Observed MW.

62 kDa

Uniprot ID

Q9Y5C1, Q9R182

 


 

Applications

 

Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

heart, liver, kidney, liver cancer

 


 

Background

 

Angiopoietin-like protein 3 (Angptl3) functions as a potent lipoprotein lipase inhibitor and is an important component of plasma triglyceride homeostasis. Angptl3 also plays a role in adipose formation and angiogenesis through its interaction with integrin ?v)beta(3). It is secreted by the liver and is functionally defined by the C-terminal fibrinogen (FBN)-like domain and an N-terminal coiled-coil domain. Angptl3 regulates circulating triglyceride levels during different nutritional states thereby mediating the feeding/fasting cycle. A deficiency of Angptl3 results in abnormally low lipid levels, and a repression of the protein may be protective against atherosclerosis. Angptl3 may also play an important role in hyperlipidemia in diabetes.

 


 

Images

 

图片 1.png

Western blot analysis of ANGPTL3 (GB112486) at dilution of 1: 1000

Lane 1: Human liver cancer tissue lysate

Lane 2: Mouse heart tissue lysate

Lane 3: Mouse liver tissue lysate

Lane 4: Mouse kidney tissue lysate

Lane 5: Rat heart tissue lysate

Lane 6: Rat liver tissue lysate

Lane 7: Rat kidney tissue lysate

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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