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GB112422 Anti -AGXT2L2 Rabbit Polyclonal Antibody for Western Blot

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse AGXT2L2
Isotype: IgG
Purity: Affinity purification
ul:
  • GB112422
  • Servicebio

Description

Product Information


Description

AGXT2L2 rabbit polyclonal

Protein full name

5-phosphohydroxy-L-lysine phospho-lyase

Synonyms

lanine--glyoxylate aminotransferase 2-like 2, Phykpl, Agxt2l2

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse AGXT2L2

Isotype

IgG

Purity

Affinity purification

Predicted MW.

52 kDa

Observed MW.

55 kDa

Uniprot ID

Q8IUZ5, Q8R1K4




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 1000-1: 2000

brain, spinal cord




Background


AGXT2 protects from asymmetric dimethylarginine (ADMA)-induced inhibition in nitric oxide (NO) production. Elevated blood concentrations of ADMA, a methyl derivate of the amino acid arginine and an endogenous inhibitor of nitric oxide (NO) synthase, is produced by the physiological degradation of methylated proteins and is found in association with diabetes, hypertension, congestive heart failure and atherosclerosis. AGXT2L2 (alanine-glyoxylate aminotransferase 2-like 2) is a 450 amino acid pyridoxal phosphate that exists as a homotetramer. Belonging to the class-III pyridoxal-phosphate-dependent aminotransferase family, AGXT2L2 localizes to the mitochondria and exists as three alternatively spliced isoforms.




Images


图片 1.png

Western blot analysis of AGXT2L2 (GB112422) at dilution of 1: 2000

Lane 1: HeLa cell lysate

Lane 2: HepG2 cell lysate

Lane 3: K562 cell lysate

Lane 4: Mouse brain tissue lysate

Lane 5: Mouse spinal cord tissue lysate

Lane 6: Rat brain tissue lysate

Lane 7: Rat spinal cord tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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