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GB112427 Anti -KDM1/LSD1 Kiaa0601 Kdm1a Aof2 Lsd1 Rabbit Polyclonal Antibody

Immunogen: Recombinant protein corresponding to Mouse KDM1/LSD1
Isotype: IgG
Purity: Affinity purification
ul:
  • GB112427
  • Servicebio

Description

Product Information

 

Description

KDM1/LSD1 rabbit polyclonal

Protein full name

Lysine-specific histone demethylase 1A

Synonyms

BRAF35-HDAC complex protein BHC110, Flavin-containing amine oxidase domain-containing protein 2, Kdm1a, Aof2, Kiaa0601, Lsd1

Immunogen

Recombinant protein corresponding to

Mouse KDM1/LSD1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus

Predicted MW.

93 kDa

Observed MW.

110 kDa

Uniprot ID

O60341, Q6ZQ88


 

Applications

 

Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

testis, placenta

IHC

Human, Mouse

1: 1500-1: 3000

lung cancer, placenta, lung, testis, heart

IF

Human, Mouse

1: 1000-1: 2000

breast cancer, testis, placenta


 

Background

 

Gene activation and repression is specifically regulated by histone methylation status at distinct lysine residues. Lysine specific demethylase 1 (KDM1/LSD1) is a long-sought histone demethylase that specifically demethylates mono and di methyl histone H3 at K4 and K9. Thus KDM1 is a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor.

 


 

Images

 

image.png

Western blot analysis of LSD1 (GB112427) at dilution of 1: 3000

Lane 1: MCF7 cell lysate

Lane 2: A549 cell lysate

Lane 3: HT29 cell lysate

Lane 4: Mouse testis tissue lysate

Lane 5: Mouse placenta tissue lysate

Lane 6: Rat placenta tissue lysate

Immunohistochemistry analysis of paraffin-embedded human lung cancer using LSD1 (GB112427) at dilution of 1: 3000

Immunohistochemistry analysis of paraffin-embedded human placenta using 

LSD1 (GB112427) at dilution of 1: 3000

Immunohistochemistry analysis of paraffin-embedded mouse placenta using 

LSD1 (GB112427) at dilution of 1: 3000

Immunohistochemistry analysis of paraffin-embedded mouse lung using 

LSD1 (GB112427) at dilution of 1: 3000

Immunohistochemistry analysis of paraffin-embedded mouse testis using 

LSD1 (GB112427) at dilution of 1: 3000

Immunohistochemistry analysis of paraffin-embedded mouse heart using 

LSD1 (GB112427) at dilution of 1: 3000

Immunofluorescent analysis of paraformaldehyde-fixed human breast cancer using LSD1 (GB112427) at dilution of 1: 2000

Immunofluorescent analysis of paraformaldehyde-fixed mouse testis using LSD1 (GB112427) at dilution of 1: 2000

Immunofluorescent analysis of paraformaldehyde-fixed mouse placenta using LSD1 (GB112427) at dilution of 1: 2000

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 

NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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