Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. Zinc finger protein 682 (ZNF682) is a 498 amino acid member of the Krueppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZNF682 contains eleven C2H2-type zinc fingers and one KRAB domain through which it is thought to be involved in DNA-binding and transcriptional regulation. Two isoforms of ZNF682 exist as a result of alternative splicing events.
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