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Anti -Twinkle Rabbit pAb for WB IHC IF primary antibody

Specification: 100uL
Applications:WB、IHC、IF
  • GB112301
  • Servicebio
  • Servicebio

Description

Product Information

Description

Twinkle rabbit polyclonal

Protein full name

Twinkle protein, mitochondrial

Synonyms

Progressive external ophthalmoplegia 1 protein homolog, T7 gp4-like protein with intramitochondrial nucleoid localization, T7-like mitochondrial DNA helicase, Twinkle mtDNA helicase, Twnk, Peo1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Twinkle

Isotype

IgG

Purity

Affinity purification

Subcellular location

Mitochondrion

Predicted MW.

77 kDa

Observed MW.

72 kDa

Uniprot ID

Q8CIW5


 

Applications

 

Applications

Species

Dilution

Positive Tissue

WB

Rat

1: 500-1: 1000

pancreas

IHC

Mouse, Rat

1: 500-1: 1000

kidney

IF

Mouse, Rat

1: 800-1: 1600

kidney


 

Background

 

Involved in mitochondrial DNA (mtDNA) metabolism. Could function as an adenine nucleotide-dependent DNA helicase. Function inferred to be critical for lifetime maintenance of mtDNA integrity. In vitro, forms in combination with POLG, a processive replication machinery, which can use double-stranded DNA (dsDNA) as template to synthesize single-stranded DNA (ssDNA) molecules. May be a key regulator of mtDNA copy number in mammals.

 


 

Images

 

图片 1.png

Western blot analysis of Twinkle (GB112301) at dilution of 1: 1000

Lane 1: Rat pancreas tissue lysate

图片 2.png

Immunohistochemistry analysis of paraffin-embedded mouse kidney using 

Twinkle (GB112301) at dilution of 1: 3000

图片 3.png

Immunofluorescent analysis of paraformaldehyde-fixed rat kidney using 

Twinkle (GB112301) at dilution of 1: 800

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 

NOTE: This product is intended for research only.

downLoadImgSlice 13Slice 10Laboratory(1)Slice 12

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