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Anti -TANK/TRAF2 Rabbit pAb For WB Immunofluorescence primary antibody

Specification: 100uL
Applications:WB 、 IF
  • GB112338
  • Servicebio
  • Servicebio

Description

Product Information

 

Description

TANK/TRAF2 rabbit polyclonal

Protein full name

TRAF family member-associated NF-kappa-B activator

Synonyms

TRAF-interacting protein, I-TRAF, Tank, Itraf

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse TRAF2

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm

Predicted MW.

51 kDa

Observed MW.

45 kDa

Uniprot ID

Q92844, P70347


 

Applications

 

Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

brain, heart

IF

Human

1: 500-1: 1000

liver cancer, colon cancer, para-cancer kidney


 

Background

 

Acts as a regulator of TRAF function by maintaining them in a latent state. Overexpression inhibits TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation. May be involved in I-kappa-B-kinase (IKK) regulation; may function as an adapter for kinases such as TBK1 or IKBKE that can modulate IKK activity.

 


 

Images

 

image.png

Western blot analysis of TRAF2 (GB112338) at dilution of 1: 1000

Lane 1: Mouse brain tissue lysate

Lane 2: Mouse heart tissue lysate

Lane 3: Rat brain tissue lysate

Lane 4: Rat heart tissue lysate

Immunofluorescent analysis of paraformaldehyde-fixed human liver cancer using TRAF2 (GB112338) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed human colon cancer using TRAF2 (GB112338) at dilution of 1: 1000

Immunofluorescent analysis of paraformaldehyde-fixed human para-cancer kidney using TRAF2 (GB112338) at dilution of 1: 1000

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 

NOTE: This product is intended for research only.

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