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Anti -beta Actin Rabbit PAb loading control antibody for WB

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Anti -beta Actin Rabbit PAb
specification:100ul
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  • GB11001
  • Servicebio
  • Servicebio

Product Information


Description

beta Actin rabbit polyclonal

Protein full name

Actin, cytoplasmic 1

Synonym

ACTB, BRWS1, PS1TP5BP1, Beta-actin, actin beta, Beta Cytoskeletal Actin

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse β-Actin

Isotype IgG
Predicted MW. 42 kDa

Observed MW.

45 kDa

Purity

Affinity purification

Uniprot ID

P60710




Applications


Applications

Species

Dilution

Positive Sample

WB

Human, Mouse, Rat

1: 1000-1: 2000

lung, kidney, brain

IHC/IF

Human, Mouse, Rat

1: 500-1: 1000

colon cancer, liver

ICC/IF

Human, Mouse, Rat

1: 300-1: 1000

NIH/3T3, A549, etc.




Background


Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility .




Images






Western blot analysis of beta-Actin (GB11001) at dilution of 1: 1000

Immunofluorescence of paraffin embedded human colon cancer using beta-Actin (GB11001) at dilution of 1: 1000

Storage



Storage

Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.

Storage Buffer

PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE:This product is intended for research only.

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Theranostics

IF: 11.556   Time: 2021   Theranostics
Chen, M.-L. et al Inhibition of miR-331-3p and miR-9-5p ameliorates Alzheimer's disease by enhancing autophagy.Theranostics 11,2395-2409(2021).PMID 33500732 Application: WB IF 11.556

Gut microbes

IF: 10.245   Time: 2021   Gut microbes
Shi, Y. et al Host Gasdermin D restrains systemic endotoxemia by capturing Proteobacteria in the colon of high-fat diet-feeding mice.Gut microbes 13,1946369-1946369(2021).PMID 34275417 Application: WB IF 10.245

Journal of neuroinflammation

IF 5.722  Time: 2021   Journal of neuroinflammation
Ma, X. et al Regulatory T cells protect against brain damage by alleviating inflammatory response in neuromyelitis optica spectrum disorder. Journal of neuroinflammation 18,201-201(2021).PMID 34526069 Application: WB IF 8.322

Cancer cell international

IF 5.722   Time: 2021   Cancer cell international

Yuan, C. et al miR-198 inhibits the progression of renal cell carcinoma by targeting BIRC5.Cancer cell international 21,390-390(2021).PMID 34289837 Application: WB IF 5.722

Journal of cellular and molecular medicine

IF 5.31   Time: 2021   Journal of cellular and molecular medicine

Chen, H. et al Potential role of FoxO3a in the regulation of trophoblast development and pregnancy complications.Journal of cellular and molecular medicine 25,4363-4372(2021).PMID 33811439 Application: WB IF 5.31

Journal of Cell Science

IF 5.285   Time: 2020   Journal of Cell Science 

Hua, R. et al Ssc-miR-21-5p regulates endometrial epithelial cell proliferation, apoptosis and migration via the PDCD4/AKT pathway.Journal of Cell Science 133,jcs248898(2020).PMID 33097608 Application: WB IF 5.285

Journal of immunology research

IF 4.818   Time: 2020   Journal of immunology 

Wang, X., Wang, F., Zhang, Z.-G., Yang, X.-M. & Zhang, RSTK3 Suppresses Ovarian Cancer Progression by Activating NF-κB Signaling to Recruit CD8(+) T-Cells.Journal of immunology research 2020,7263602-7263602(2020).PMID 33062724 Application: WB IF 4.818

Pharmaceutical biology

IF 3.503   Time: 2021   Pharmaceutical biology

Pi, X.-J. et al Saponins from Panax japonicus attenuate cognitive impairment in ageing rats through regulating microglial polarisation and autophagy.Pharmaceutical biology 59,1117-1125(2021).PMID 34403300 Application: WB IF 3.503

Molecular medicine reports

IF 2.952   Time: 2021   Molecular medicine reports

Jiang, F. et al Fluorofenidone attenuates paraquat‑induced pulmonary fibrosis by regulating the PI3K/Akt/mTOR signaling pathway and autophagy.Molecular medicine reports 23,405(2021).PMID 33786626 Application: WB IF 2.952

Molecular medicine reports

IF 2.952   Time: 2021   Molecular medicine reports

Liu, C. et al Serum‑derived exosomes from house dust mite‑sensitized guinea pigs contribute to inflammation in BEAS‑2B cells via the TLR4‑NF‑κB pathway.Molecular medicine reports 24,747(2021).PMID 34458929 Application: WB IF 2.952


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