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Anti -CD45 Rabbit pAb

Cat. No. GB11066

Brand:Servicebio

Price:230.00

Specification: 100μL

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Product Information

Description

CD45 rabbit polyclonal

Protein full name

Receptor-type tyrosine-protein phosphatase C

Synonyms

PTPRC, B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200, protein tyrosine phosphatase, receptor type C

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse CD45

Isotype IgG
Purity Affinity purification
Subcellular location

Membrane,Membrane raft

Uniprot ID P06800,P04157


Applications

Applications

IHC,IF

Species Mouse
Dilution 1:1000-1:1500
Positive tissue

spleen,lung,liver


Background

Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.


Images

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Immunohistochemistry analysis of paraffin-embedded mouse liver using CD45(GB11066) at dilution of 1:1500

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Immunohistochemistry analysis of paraffin-embedded mouse lung using CD45(GB11066) at dilution of 1:1000

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Immunohistochemistry analysis of paraffin-embedded mouse spleen using CD45(GB11066) at dilution of 1:1500


Storage

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

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