Product Information
| Description | CD68 rabbit polyclonal |
| Protein full name | Macrosialin |
| Synonyms | CD68,CD68 Molecule,Scavenger Receptor Class D, Member 1 ,Macrophage Antigen CD68,GP110 ,Macrosialin,SCARD1, LAMP4 |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse CD68 |
| Isotype | IgG |
| Purity | Affinity purification |
| Subcellular location | Cell membrane,Endosome membrane, Lysosome membrane |
| Uniprot ID | P31996 |
Applications
| Applications | IHC, IF |
| Species | Mouse,Rat |
| Dilution | 1:500-1:1000 |
| Positive tissue | Spleen, liver |
Background
Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
Images
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| Immunohistochemistry analysis of paraffin-embedded mouse lung using CD68 (GB11067) at dilution of 1:500 |
 | Immunohistochemistry analysis of paraffin-embedded rat liver using CD68 (GB11067) at dilution of 1:1000
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 | Immunohistochemistry analysis of paraffin-embedded mouse spleen using CD68(GB11067) at dilution of 1:1000
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| Immunofluorescent analysis of paraformaldehyde-fixed mouse bone using CD68(GB11067) at dilution of 1:1000 |
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| Immunohistochemistry analysis of paraffin-embedded rat lymph node using CD68(GB11067) at dilution of 1:1000 |
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| Immunohistochemistry analysis of paraffin-embedded rat spleen using CD68(GB11067) at dilution of 1:1000 |
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
NOTE: This product is intended for research only.