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Anti -CD8 alpha Rabbit pAb

Cat. No. GB11068

Brand:Servicebio

Price:230.00

Specification: 100μLDiscontinued

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Product Information

 

 

Description

CD8 alpha rabbit polyclonal

Protein full name

T-cell surface glycoprotein CD8 alpha chain

Synonyms

CD8A, CD8, Leu2, MAL, p32,CD8a molecule, CD8 alpha

Immunogen KLH conjugated Synthetic peptide corresponding to Mouse CD8A
Isotype IgG
Purity Affinity purification
Subcellular location

Cell membrane,Secreted

Uniprot ID P01731,P07725

 


 

Applications

 

 

Applications

IHC

IF

Species Mouse,Rat Mouse,Rat
Dilution

1:500-1:2000

1:200-1:1000

Positive tissue spleen

spleen

 


 

Background

 

 

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.

 


 

Images

 

 

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Immunofluorescence analysis of paraffin-embedded mouse spleen using CD8A(GB11068) at dilution of 1:200

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Immunohistochemistry analysis of paraffin-embedded mouse spleen using CD8A(GB11068) at dilution of 1:1500

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Immunohistochemistry analysis of paraffin-embedded rat spleen using CD8A(GB11068) at dilution of 1:1500

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

 


 

NOTE: This product is intended for research only.