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Anti -Ki67 Rabbit PAb for Cancer Research IHC IF Primary Antibody

specification:100ul
  • GB111499
  • Servicebio
  • Servicebio

Description

Product Information


Description

Ki67 rabbit polyclonal

Protein full name

Proliferation marker protein Ki-67

Synonyms

MKI67, marker of proliferation Ki-67, KIA,

MIB-1, PPP1R105

Immunogen

KLH conjugated Synthetic peptide

corresponding to Human Ki67

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus

Uniprot ID

P46013, E9PVX6




Applications


applications

species

dilution

Positive tissue

IHC

Human,

Mouse, Rat

1: 200-1: 400

colon cancer, esophageal cancer, tumor cell subcutaneous, ovary, small intestine




Background

Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226). Binds DNA, with a preference for supercoiled DNA and AT-rich DNA (By similarity).




Images



Immunohistochemistry analysis of paraffin-embedded human colon cancer using Ki67 (GB111499) at dilution of 1: 750

image.png

Immunohistochemistry analysis of paraffin-embedded human esophageal cancer using Ki67 (GB111499) at dilution of 1: 750

Immunohistochemistry analysis of paraffin-embedded human tumor cell subcutaneous using Ki67 (GB111499) at dilution of 1: 600

Immunohistochemistry analysis of paraffin-embedded mouse ovary using

Ki67 (GB111499) at dilution of 1: 500


Immunohistochemistry analysis of paraffin-embedded mouse small intestine using Ki67 (GB111499) at dilution of 1: 750

Immunohistochemistry analysis of paraffin-embedded rat small intestine using Ki67 (GB111499) at dilution of 1: 500




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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