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GB111751 Anti -IQGAP3 MGC1947 Rabbit Polyclonal Antibody for IHC

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Immunogen: Recombinant protein corresponding to Human IQGAP3
Isotype: IgG
Purity: Affinity purification

 

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Product Information


Description

IQGAP3 rabbit polyclonal

Protein full name

Ras GTPase-activating-like protein IQGAP3

Synonyms

IQGAP3, IQ motif containing GTPase activating protein 3, MGC1947

Immunogen

Recombinant protein corresponding to

Human IQGAP3

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membrane, Cytoplasm

Uniprot ID

Q86VI3




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Human

1: 700-1: 1400

lung, placenta




Background


IQGAP3 (IQ motif containing GTPase activating protein 3) is a 1,631 amino acid protein that acts as an effector of Cdc42 and Rac 1, linking their activation to the cytoskeleton during neuronal morphogenesis. A novel member of the IQGAP family, IQGAP3 is highly expressed in brain where it localizes to axons of hippocampal neurons. IQGAP3 contains one Ras-GAP domain, a CH (calponin-homology) domain, four IQ domains and is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.




Images


Immunohistochemistry analysis of paraffin-embedded human lung using

IQGAP3 (GB111751) at dilution of 1: 1400

Immunohistochemistry analysis of paraffin-embedded human placenta using

IQGAP3 (GB111751) at dilution of 1: 1400




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer(G2025).

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