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GB112101 Anti -DOCK2 Protein Hch KIAA0209 Rabbit Polyclonal Antibody for WB

Immunogen: Recombinant protein corresponding to Mouse DOCK2
Isotype: IgG
Purity: Affinity purification
ul:
  • GB112101
  • Servicebio

Description

Product Information


Description

DOCK2 rabbit polyclonal

Protein full name

Dedicator of cytokinesis protein 2

Synonyms

Protein Hch, Dock2, Dedicator of cyto kinesis 2, KIAA0209, Dedicator of cytokinesis 2

Immunogen

Recombinant protein corresponding to

Mouse DOCK2

Isotype

IgG

Purity

Affinity purification

Predicted MW.

212 kDa

Observed MW.

220 kDa

Uniprot ID

Q92608, Q8C3J5




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

lymph gland, spleen




Background


The DOCK2 gene encodes dedicator of cytokinesis 2 (DOCK 2), a hematopoietic cell-specific CDM family protein that is indispensable for lymphocyte chemotaxis. DOCK 2 participates in the cytoskeletal rearrangements that are required for lymphocyte migration in response of chemokines. DOCK 2 may also participate in IL-2 transcriptional activation through the activation of Rac 2. DOCK 2 contains one DHR-1 (CZH-1) domain, one DHR-2 (CZH-2) domain and one SH3 domain. The DHR-2 domain is a putative GEF activity mediator. The DOCK 2 protein also co-localizes with F-Actin, and demonstrates expression in several human tissues, with the highest levels observed in peripheral blood leukocytes, thymus, spleen and liver.




Images


图片 2.png

Western blot analysis of DOCK2 (GB112101)

at dilution of 1: 1000

Lane 1: Jurkat cell lysate

Lane 2: THP-1 cell lysate

Lane 3: Mouse lymph gland tissue lysate

Lane 4: Mouse spleen tissue lysate

Lane 5: Rat lymph gland tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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