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GB112106 Anti -SYT1 Synaptotagmin I FLJ42519 Rabbit Polyclonal Antibody for WB

Immunogen: Recombinant protein corresponding to Mouse SYT1
Isotype: IgG
Purity: Affinity purification
ul:
  • GB112106
  • Servicebio

Description

Product Information



Description

SYT1 rabbit polyclonal

Protein full name

Synaptotagmin-1

Synonyms

Synaptotagmin I, SytI, p65, DKFZp781D2042, FLJ42519, SVP65, Syt2

Immunogen

Recombinant protein corresponding to

Mouse SYT1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

47 kDa

Observed MW.

60 kDa

Uniprot ID

P46096, P21707





Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

brain, cortex



Background


The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin participates in triggering neurotransmitter release at the synapse. Synaptotagmin may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.




Images


图片 1.png

Western blot analysis of SYT1 (GB112106)

at dilution of 1: 1000

Lane 1: Mouse brain tissue lysate

Lane 2: Mouse cortex tissue lysate

Lane 3: Rat brain tissue lysate

Lane 4: Rat cortex tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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