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GB11212 Anti -IKB Alpha NFKBI IKBA NFKB Inhibitor Rabbit Polyclonal Antibody for IHC IF

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse IKBα
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11212
  • Servicebio

Description

Product Information


Description

IKB alpha rabbit polyclonal

Protein full name

NF-kappa-B inhibitor alpha

Synonyms

NFKBIA, IKBA, MAD-3, NFKBI, NFKB inhibitor alpha

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse IKBα

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus

Uniprot ID

P25963, Q9Z1E3




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Human

1: 500-1: 1000

lung cancer, liver cancer, stomach cancer

IF

Human

1: 500-1: 1000

lung cancer, liver cancer, stomach cancer




Background


Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.




Images



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Immunohistochemistry analysis of paraffin-embedded human lung cancer using IKBα (GB11212) at dilution of 1: 1000

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Immunohistochemistry analysis of paraffin-embedded human colon cancer using IKBα (GB11212) at dilution of 1: 1000


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Immunohistochemistry analysis of paraffin-embedded human stomach cancer using IKBα (GB11212) at dilution of 1: 1000




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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