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GB112135 Anti -uPA Receptor U-PAR Plaur Rabbit Polyclonal Antibody for WB

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse U-PAR
Isotype: IgG
Purity: Affinity purification
ul:
  • GB112135
  • Servicebio

Description

Product Information


Description

uPA Receptor/U-PAR rabbit polyclonal

Protein full name

Urokinase plasminogen activator surface receptor

Synonyms

U-PAR, CD87, Plaur, MO3, URKR, UPA receptor, Plasminogen activator urokinase receptor

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse U-PAR

Isotype

IgG

Purity

Affinity purification

Predicted MW.

35 kDa

Observed MW.

50 kDa

Uniprot ID

Q03405, P35456, P49616




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

heart, kidney, brain




Background


This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus.




Images


图片 1.png

Western blot analysis of U-PAR (GB112135)

at dilution of 1: 1000

Lane 1: A431 cell lysate

Lane 2: Mouse heart tissue lysate

Lane 3: Mouse kidney tissue lysate

Lane 4: Mouse brain tissue lysate

Lane 5: Rat heart tissue lysate

Lane 6: Rat kidney tissue lysate

Lane 7: Rat brain tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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