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GB112139 Anti -CD32 Fcgr2 Fcgr2b FcRII Rabbit Polyclonal Antibody for WB

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse CD32
Isotype: IgG
Purity: Affinity purification
ul:
  • GB112139
  • Servicebio

Description

Product Information


Description

CD32 rabbit polyclonal

Protein full name

Low affinity immunoglobulin gamma Fc region receptor II

Synonyms

Fc gamma receptor IIB, Fc-gamma RII, Fc-gamma-RIIB, FcRII, IgG Fc receptor II beta, Lymphocyte antigen 17, Ly-17, CD32, Fcgr2, Fcgr2b

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse CD32

Isotype

IgG

Purity

Affinity purification

Predicted MW.

37 kDa

Observed MW.

40 kDa

Uniprot ID

P08101, Q63203




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 250-1: 500

liver




Background


Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of antigen-antibody complexes from the circulation and modulation of antibody production by B-cells. Isoform IIB1 and isoform IIB1' form caps but fail to mediate endocytosis or phagocytosis. Isoform IIB2 can mediate the endocytosis of soluble immune complexes via clathrin-coated pits. Isoform IIB1 and isoform IIB2 can down-regulate B-cell, T-cell, and mast cell activation when coaggregated to B-cell receptors for AG (BCR), T-cell receptors for AG (TCR), and Fc receptors, respectively.




Images


图片 1.png

Western blot analysis of CD32 (GB112139) at dilution of 1: 500

Lane 1: Mouse liver tissue lysate

Lane 2: Rat liver tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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