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Anti -STRAD Rabbit pAb Western blot antibody Tumor markers

Specification: 100uL
Applications:WB
Species:Human, Mouse, Rat
  • GB112208
  • Servicebio
  • Servicebio

Description

Product Information


Description

STRAD rabbit polyclonal

Protein full name

STE20-related kinase adapter protein alpha

Synonyms

STRAD alpha, STE20-related adapter protein, Strada, Lyk5, Strad

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse STRAD

Isotype

IgG

Purity

Affinity purification

Predicted MW.

48 kDa

Observed MW.

48 kDa

Uniprot ID

Q7RTN6, Q3UUJ4, Q7TNZ6





Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

112208




Background


LYK5 is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating the tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. LYK5-LKB1 interaction results in phosphorylation of LYK5 and enhanced autophosphorylation of LKB1.




Images


图片 1.png

Western blot analysis of STRAD (GB112208)

at dilution of 1: 1000

Lane 1: A549 cell lysate

Lane 2: HepG2 cell lysate

Lane 3: Mouse brain tissue lysate

Lane 4: Rat brain tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

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