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Anti -EPCR/CD201 Rabbit pAb Western blot antibody

Specification: 100uL
Applications:WB
Species:Human
  • GB112210
  • Servicebio
  • Servicebio

Description

Product Information


Description

EPCR/CD201 rabbit polyclonal

Protein full name

Endothelial protein C receptor

Synonyms

Activated protein C receptor, APC receptor, Centrocyclin, Centrosomal protein CCD41, Endothelial cell protein C receptor, CD201, Procr, Epcr

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse CD201

Isotype

IgG

Purity

Affinity purification

Predicted MW.

27 kDa

Observed MW.

46 kDa

Uniprot ID

Q9UNN8




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human

1: 500-1: 1000

A549, HT-29, THP-1




Background


EPCR is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. It is an N glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. It is expressed strongly in the endothelial cells of arteries and veins in heart and lung. It is overexpressed in several human non-Pgp multidrug resistant (MDR) tumor cell lines. Whether and how anti-coagulant and anti-inflammatory functions of EPCR facilitate oncogenesis and/or drug resistance is unclear.




Images


图片 1.png

Western blot analysis of CD201 (GB112210) at dilution of 1: 1000

Lane 1: A549 cell lysate

Lane 2: HT-29 cell lysate

Lane 3: THP-1 cell lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

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