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Anti -HNF1 alpha Rabbit pAb Western blot antibody

Specification: 100uL
Applications:WB
Species:Mouse, Rat
  • GB112214
  • Servicebio
  • Servicebio

Description

Product Information


Description

HNF1 alpha rabbit polyclonal

Protein full name

Hepatocyte nuclear factor 1-alpha

Synonyms

HNF-1-alpha, HNF-1A, Liver-specific transcription factor LF-B1, LFB1, Transcription factor 1, TCF-1, Hnf-1, Hnf-1a, Tcf1, Hnf1a

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse HNF1 alpha

Isotype

IgG

Purity

Affinity purification

Predicted MW.

57 kDa

Observed MW.

81 kDa

Uniprot ID

P22361, P15257




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

pancreas, prostate, liver




Background


The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms.




Images


图片 1.png

Western blot analysis of HNF1 alpha (GB112214) at dilution of 1: 1000

Lane 1: Mouse pancreas tissue lysate

Lane 2: Mouse prostate tissue lysate

Lane 3: Rat liver tissue lysate

Lane 4: Rat pancreas tissue lysate

图片 3.png

Western blot analysis of HNF1 alpha (GB112214) at dilution of 1: 1000

Lane 1: Mouse pancreas tissue lysate

Lane 2: Mouse prostate tissue lysate

Lane 3: Rat pancreas tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

downLoadImgSlice 13Slice 10Laboratory(1)Slice 12

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