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Anti -PAK2 Rabbit PAb Western Blot Antibody

Specification: 100uL
Applications:WB
Species:Human, Mouse, Rat
  • GB112217
  • Servicebio
  • Servicebio

Description

Product Information


Description

PAK2 rabbit polyclonal

Protein full name

Serine/threonine-protein kinase PAK 2

Synonyms

Gamma-PAK, p21-activated kinase 2, PAK-2, Pak2, C-t-PAK2, CB422, PAK-2p34, p27, p34, PAKgamma

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse PAK2

Isotype

IgG

Purity

Affinity purification

Predicted MW.

58 kDa

Observed MW.

58 kDa

Uniprot ID

Q13177, Q8CIN4, Q64303




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

spleen, ovary




Background


The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase mediated apoptosis, PAK2 also interacts with and is activated by HIV1 Nef.




Images


图片 1.png

Western blot analysis of PAK2 (GB112217)

at dilution of 1: 1000

Lane 1: HEK293 cell lysate

Lane 2: NIH3T3 cell lysate

Lane 3: A431 cell lysate

Lane 4: Jurkat cell lysate

Lane 5: Mouse spleen tissue lysate

Lane 6: Mouse ovary tissue lysate

Lane 7: Rat ovary tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

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