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Anti -ALK-1 Rabbit pAb Polyclonal antibody for WB

Specification: 100uL
Applications:WB
Species:Human, Mouse, Rat
  • GB112218
  • Servicebio
  • Servicebio

Description

Product Information


Description

ALK-1 rabbit polyclonal

Protein full name

Serine/threonine-protein kinase receptor R3

Synonyms

SKR3, Activin receptor-like kinase 1, ALK-1, TGF-B superfamily receptor type I, TSR-I, Acvrl1, Acvrlk1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse ALK-1

Isotype

IgG

Purity

Affinity purification

Predicted MW.

57 kDa

Observed MW.

57 kDa

Uniprot ID

P37023, Q61288, P80203




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

kidney, liver, lung




Background


This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.




Images


图片 1.png

Western blot analysis of ALK-1 (GB112218)

at dilution of 1: 1000

Lane 1: Jurkat cell lysate

Lane 2: Mouse kidney tissue lysate

Lane 3: Mouse liver tissue lysate

Lane 4: Mouse lung tissue lysate

Lane 5: Rat kidney tissue lysate

Lane 6: Rat liver tissue lysate

Lane 7: Rat lung tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

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