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Anti -SerpinB2/PAI-2 Rabbit pAb Western blot antibody

Specification: 100uL
Applications:WB
Species:Human, Mouse
  • GB112219
  • Servicebio
  • Servicebio

Description

Product Information


Description

SerpinB2/PAI-2 rabbit polyclonal

Protein full name

Plasminogen activator inhibitor 2, macrophage

Synonyms

PAI-2, Serpin B2, Serpinb2, Pai2, Planh2, Monocyte Arginine-serpin, Urokinase inhibitor

Immunogen

Recombinant protein corresponding to Mouse SerpinB2/PAI-2

Isotype

IgG

Purity

Affinity purification

Predicted MW.

46 kDa

Observed MW.

42 kDa

Uniprot ID

P05120, P12388




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse

1: 500-1: 1000

cortex




Background


SerpinB2 is a serine proteinase inhibitor of the ovalbumin like B clade of serpins. It was first discovered in the placenta, and given the name PAI-2 because of the ability to inhibit urokinase plasminogen activator (u-PA) at low micromolar efficiency. SerpinB2 also inhibits tissue plasminogen activator (t-PA), but with micromolar efficiency, and PAI-1 is much more efficient that SerpinB2 on both forms of plasminogen activator. The structure of PAI-2 is not terribly similar to PAI-1, however, which is an E clade serpin.




Images


图片 1.png

Western blot analysis of PAI-2 (GB112219) at dilution of 1: 1000

Lane 1: MCF7 cell lysate

Lane 2: Mouse cortex tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

downLoadImgSlice 13Slice 10Laboratory(1)Slice 12

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