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Anti -BNC1/BNC Rabbit pAb Western blot antibody

Specification: 100uL
  • GB112247
  • Servicebio
  • Servicebio

Description

Product Information


Description

BNC1/BNC rabbit polyclonal

Protein full name

Zinc finger protein basonuclin-1

Synonyms

Bnc1, Bnc, basonuclin 1, BSN1, basonuclin, HsT19447

Immunogen

Recombinant protein corresponding to Mouse BNC1/BNC

Isotype

IgG

Purity

Affinity purification

Predicted MW.

107 kDa

Observed MW.

107 kDa

Uniprot ID

Q01954, O35914




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 250-1: 500

testis, ovary




Background


The zinc finger protein, basonuclin, is a putative rDNA transcription factor with highly restricted tissue distribution. Basonuclin is abundantly expressed in keratinocytes of the basal layer of the epidermis, the outer sheath of hair follicles and in the germ cells of the testis and ovary. In the epidermis, basonuclin, which is mainly localized to the cytoplasm, translocates to basal cell nuclei during different stages of keratinocyte growth. Basonuclin may enhance rRNA synthesis by elevating transcription from an rDNA promoter and inhibiting RNA polymerase I transcription through its zinc finger domain. Therefore, basonuclin may be a cell-type-specific transcription factor for rDNA transcription.




Images


图片 1.png

Western blot analysis of BNC1(GB112247) at dilution of 1: 500

Lane 1: HepG2 cell lysate

Lane 2: HaCaT cell lysate

Lane 3: Mouse testis tissue lysate

Lane 4: Rat testis tissue lysate

Lane 5: Rat ovary tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

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