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Anti -TRIP13/PCH2 Rabbit PAb Polyclonal Antibody for Western Blot

Specification: 100uL
  • GB112248
  • Servicebio
  • Servicebio

Description

Product Information


Description

TRIP13/PCH2 rabbit polyclonal

Protein full name

Pachytene checkpoint protein 2 homolog

Synonyms

Thyroid hormone receptor interactor 13, Thyroid receptor-interacting protein 13, TR-interacting protein 13, TRIP-13, Trip13, Pch2, 16E1BP, HPV16 E1 protein-binding protein

Immunogen

Recombinant protein corresponding to Mouse TRIP13/PCH2

Isotype

IgG

Purity

Affinity purification

Predicted MW.

48 kDa

Observed MW.

48 kDa

Uniprot ID

Q15645, Q3UA06, Q5XHZ9




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

testis, pancreas




Background


Thyroid hormone receptors (TRs) are transcription factors that regulate the expression of specific genes in a hormone-dependent manner. TRIP13 is a transcription factor that interacts with the ligand binding domain of the thyroid receptor (TR) as well as a variety of target genes including human papilloma virus type 16 (HPV16) E1. Unlike most TRIP proteins which function only in the presence of hormones, TRIP13 does not require the presence of thyroid hormone to interact with TR. The association of TRIP13 with (HPV16) E1 suggests that TRIP13 may have tumor suppressor gene function. TRIP13 is a 432 amino acid protein with 2 different isoforms produced by alternative splicing.




Images


图片 1.png

Western blot analysis of TRIP13 (GB112248) at dilution of 1: 1000

Lane 1: Caco2 cell lysate

Lane 2: NIH-3T3 cell lysate

Lane 3: HeLa cell lysate

Lane 4: 293T cell lysate

Lane 5: Jurkat cell lysate

Lane 6: Mouse testis tissue lysate

Lane 7: Mouse pancreas tissue lysate

Lane 8: Rat testis tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

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