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Anti -Myelin Basic Protein Rabbit PAb for IHC IF Western Blot MBP Antibody

Specification: 100uL
  • GB11226
  • Servicebio
  • Servicebio

Description

Product Information


Description

Myelin Basic Protein rabbit polyclonal

Protein full name

Myelin Basic Protein

Synonyms

MBP, entrez:4155, myelin basic protein

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse Myelin Basic Protein

Isotype

IgG

Purity

Affinity purification

Predicted MW.

27 kDa

Observed MW.

17/20 kDa

Subcellular location

Myelin membrane, Cytoplasmic side of myelin

Uniprot ID

P04370, P02688




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

brain

IHC

Mouse, Rat

1: 300-1: 600

brain

IF

Mouse, Rat

1: 300-1: 600

brain




Background


The classic group of MBP isoforms (isoform 4-isoform 13) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined to optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function.




Images



图片 2.png

Western blot analysis of Myelin Basic Protein (GB11226) at dilution of 1: 1000.

Lane 1: Mouse brain tissue lysate

Lane 2: Mouse hippocampus tissue lysate

Lane 3: Mouse cerebellum tissue lysate

Lane 4: Rat brain tissue lysate

Lane 5: Rat hippocampus tissue lysate

Lane 6: Rat cerebellum tissue lysate

blob.png

Immunohistochemistry analysis of paraffin-embedded mouse brain using Myelin Basic Protein (GB11226) at dilution of 1: 600

blob.png

Immunohistochemistry analysis of paraffin-embedded rat brain using Myelin Basic Protein (GB11226) at dilution of 1: 600




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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