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Anti -TIMP4 Rabbit pAb Western blot antibody

Specification: 100uL
  • GB112268
  • Servicebio
  • Servicebio

Description

Product Information


Description

TIMP4 rabbit polyclonal

Protein full name

Metalloproteinase inhibitor 4

Synonyms

Tissue inhibitor of metalloproteinases 4, TIMP-4, Timp4

Immunogen

Recombinant protein corresponding to Mouse TIMP4

Isotype

IgG

Purity

Affinity purification

Predicted MW.

26 kDa

Observed MW.

30 kDa

Uniprot ID

Q9JHB3, P81556




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

heart, brain, lung




Background


The tissue inhibitors of metalloproteinases (TIMPs) are naturally occurring proteins that specifically inhibit matrix metalloproteinases and regulate extracellular matrix turnover and tissue remodeling by forming tightbinding inhibitory complexes with the MMPs. Thus, TIMPs maintain the balance between matrix destruction and formation. An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. The TIMP proteins share several structural features including six loops held in place by six disulfide bonds arranged in three knot-like structures. 




Images


图片 1.png

Western blot analysis of TIMP4 (GB112268) 

at dilution of 1: 1000

Lane 1: NIH-3T3 cell lysate

Lane 2: Mouse heart tissue lysate

Lane 3: Mouse brain tissue lysate

Lane 4: Rat heart tissue lysate

Lane 5: Rat brain tissue lysate

Lane 6: Rat lung tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

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