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Anti -alpha 1 Antitrypsin Rabbit pAb Western blot Primary antibody

Specification: 100uL
  • GB112270
  • Servicebio
  • Servicebio

Description

Product Information


Description

alpha 1 Antitrypsin rabbit polyclonal

Protein full name

Alpha-1-antitrypsin 1-2

Synonyms

AAT, Alpha-1 protease inhibitor 2, Alpha-1-antiproteinase, Serine protease inhibitor 1-2, Serine protease inhibitor A1b, Serpin A1b, Serpina1b, Aat2, Dom2, Spi1-2

Immunogen

Recombinant protein corresponding to Human alpha 1 Antitrypsin

Isotype

IgG

Purity

Affinity purification

Predicted MW.

46 kDa

Observed MW.

55 kDa

Uniprot ID

P22599




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse

1: 500-1: 1000

liver, lung




Background


Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin. Short peptide from AAT: reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE).




Images


图片 1.png

Western blot analysis of alpha 1 Antitrypsin (GB112270) at dilution of 1: 1000

Lane 1: Mouse liver tissue lysate

Lane 2: Mouse lung tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

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