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Anti -A4GNT Rabbit pAb Western blot antibody

Specification: 100uL
Applications: WB
Species: Human, Mouse, Rat
  • GB112322
  • Servicebio
  • Servicebio

Description

Product Information


Description

A4GNT rabbit polyclonal

Protein full name

Alpha-1,4-N-acetylglucosaminyltransferase

Synonyms

Alpha4GnT, A4gnt, Alpha 1 4 N acetylglucosaminyltransferase, 4-N-acetylglucosaminyltransferase

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse A4GNT

Isotype

IgG

Purity

Affinity purification

Predicted MW.

39 kDa

Observed MW.

39 kDa

Uniprot ID

Q9UNA3, Q14BT6




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

pancreas, kidney




Background


Alpha 1,4-N-acetylflucosaminyltransferase (Alpha4Gn-T) mediates the biosynthesis of mucin type glycoprotein (O-glycan). Alpha4Gn-T acts as the key enzyme for the formation of the unique glycan GlcNAcalpha1-4Galbeta1-R, and most efficiently transfers N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Alpha4Gn-T is a single-pass type II membrane protein associated with the Golgi apparatus and contains the conserved DXD motif involved in catalytic activity. It is expressed in stomach and pancreas, as well as in gastric cancer cells. Alpha4Gn-T is not expressed in peripheral blood cells, making it a useful biomarker for pancreatic cancer.


Images


图片 1.png

Western blot analysis of A4GNT (GB112322) 

at dilution of 1: 1000

Lane 1: HeLa cell lysate

Lane 2: A549 cell lysate

Lane 3: LO2 cell lysate

Lane 4: Mouse pancreas tissue lysate

Lane 5: Mouse kidney tissue lysate

Lane 6: Rat pancreas tissue lysate

Lane 7: Rat kidney tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

downLoadImgSlice 13Slice 10Laboratory(1)Slice 12

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