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Anti -Myf5 Rabbit pAb Western blot antibody

Specification: 100uL
Applications:WB
Species:Mouse, Rat
  • GB112330
  • Servicebio
  • Servicebio

Description

Product Information


Description

Myf5 rabbit polyclonal

Protein full name

Myogenic factor 5

Synonyms

Myf-5, Myf5, bHLHc2, Class C basic helix-loop-helix protein 2

Immunogen

Recombinant protein corresponding to Mouse Myf5

Isotype

IgG

Purity

Affinity purification

Predicted MW.

28 kDa

Observed MW.

39 kDa

Uniprot ID

P24699




Applications


Applications

Species

Dilution

Positive Tissue

WB

Mouse, Rat

1: 500-1: 1000

skeletal muscle




Background


Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development include Myo D, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or herculin). Of interest, most muscle cells express either Myo D or Myf-5 in the committed state, but when induced to differentiate, all turn on expression of myogenin. Myo D transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes.




Images


图片 1.png

Western blot analysis of Myf5 (GB112330) 

at dilution of 1: 1000

Lane 1: Mouse skeletal muscle tissue lysate

Lane 2: Rat skeletal muscle tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

downLoadImgSlice 13Slice 10Laboratory(1)Slice 12

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