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Anti -CREB Rabbit pAb for IHC IF primary antibody

Specification: 100uL
applications:IHC、IF
species: Human
  • GB11236
  • Servicebio
  • Servicebio

Description

Product Information


Description

CREB rabbit polyclonal

Protein full name

Cyclic AMP-responsive element-binding protein 1

Synonyms

CREB1, CREB, CREB-1, cAMP responsive element binding protein 1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse CREB1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus

Uniprot ID

Q01147, P16220




Applications


applications

species

dilution

Positive tissue

IHC

Human

1: 200-1: 800

lung, liver, kidney

IF

Human

1: 200-1: 800

lung, liver, kidney




Background


Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.



Images



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Immunohistochemistry analysis of paraffin-embedded human lung cancer  using CREB(GB11236) at dilution of 1:400

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Immunohistochemistry analysis of paraffin-embedded human liver using CREB(GB11236) at dilution of 1:400

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Immunohistochemistry analysis of paraffin-embedded human liver cancer  using CREB(GB11236) at dilution of 1:400

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Immunohistochemistry analysis of paraffin-embedded human kidney  using CREB(GB11236) at dilution of 1:400

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Immunohistochemistry analysis of paraffin-embedded human stomach cancer using CREB(GB11236) at dilution of 1:400




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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