PHONE

+86(027) 5111 3188

Share to:

Anti -NOX2/gp91phox Rabbit pAb Western blot antibody

Specification: 100uL
Applications:WB
Species:Human, Mouse, Rat
  • GB112362
  • Servicebio
  • Servicebio

Description

Product Information


Description

NOX2/gp91phox rabbit polyclonal

Protein full name

Cytochrome b-245 heavy chain 

Synonyms

CGD91-phox, Cytochrome b(558) subunit beta, Cytochrome b558 subunit beta, Heme-binding membrane glycoprotein gp91phox, Neutrophil cytochrome b 91 kDa polypeptide, gp91-1, gp91-phox, p22 phagocyte B-cytochrome, Cybb, Cgd

Immunogen

Recombinant protein corresponding to Mouse NOX2/gp91phox

Isotype

IgG

Purity

Affinity purification

Predicted MW.

65 kDa

Observed MW.

65 kDa

Uniprot ID

P04839, Q61093




Applications


Applications

Species

Dilution

Positive Tissue

WB

Human, Mouse, Rat

1: 400-1: 800

liver




Background


NOX2/gp91phox is a critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. It also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc. Defects in CYBB are a cause of X-linked chronic granulomatous disease (X-CGD). X-CGD is characterized by the failure of activated phagocytes to generate superoxide.




Images


图片 1.png

Western blot analysis of NOX2/gp91phox (GB112362) at dilution of 1: 800

Lane 1: HeLa cell lysate

Lane 2: Mouse liver tissue lysate

Lane 3: Rat liver tissue lysate




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


NOTE: This product is intended for research only.

downLoadImgSlice 13Slice 10Laboratory(1)Slice 12

Contact us

Quick Links

Product Category

Get In Touch

 5th Floor, 22 Building, Biopark, Gaoxin 2nd Road No. 388, East Lake High-Tech Developing Zone, Wuhan, Hubei, China 430079
 +86(027) 5111 3188
Copyright © 2021  Wuhan Servicebio Technology Co., Ltd.