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Anti -BRCC45/BRE Rabbit pAb for IHC IF primary antibody

Specification: 100uL
Applications:IHC、IF
  • GB112384
  • Servicebio
  • Servicebio

Description

Product Information

 

Description

BRCC45/BRE rabbit polyclonal

Protein full name

BRISC and BRCA1-A complex member 2

Synonyms

BRCA1-A complex subunit BRE, BRCA1/BRCA2-containing complex subunit 45, Brain and reproductive organ-expressed protein, Babam2, Bre, BRCC4, BRCC45

Immunogen

KLH conjugated Synthetic peptide

corresponding to Mouse BRCC45/BRE

Isotype

IgG

Purity

Affinity purification

Subcellular location

CytoplasmNucleus

Uniprot ID

Q9NXR7, Q8K3W0, Q6P7Q1


 

Applications

 

Applications

Species

Dilution

Positive Tissue

IHC

Human, Mouse, Rat

1: 200-1: 400

glioma, placenta, brain, pancreas

IF

Human, Mouse, Rat

1: 250-1: 500

glioma, placenta, brain, pancreas


 

Background

 

BRE, also named as BRCC45, is a death receptor-associated antiapoptotic protein, which is also involved in DNA-damage repair, and K63-specific deubiquitination. BRE and its XIAP-sustaining mechanism could represent novel targets for anti-cancer therapy. BRE may regulate TNF-alpha signaling through its interactions with TNFRSF1A. It plays a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins. BRE gene has four isoforms with MW 42-47 kDa.

 


 

Images

 

 

Immunohistochemistry analysis of paraffin-embedded human glioma using 

BRE (GB112384) at dilution of 1: 200

Immunohistochemistry analysis of paraffin-embedded human placenta using 

BRE (GB112384) at dilution of 1: 200

Immunohistochemistry analysis of paraffin-embedded mouse placenta using 

BRE (GB112384) at dilution of 1: 200

Immunohistochemistry analysis of paraffin-embedded rat placenta using 

BRE (GB112384) at dilution of 1: 200

Immunohistochemistry analysis of paraffin-embedded mouse brain using 

BRE (GB112384) at dilution of 1: 200

Immunohistochemistry analysis of paraffin-embedded mouse brain of suckling mouse using BRE (GB112384) at dilution of 1: 200

Immunohistochemistry analysis of paraffin-embedded mouse pancreas using 

BRE (GB112384) at dilution of 1: 200

Immunohistochemistry analysis of paraffin-embedded rat pancreas using 

BRE (GB112384) at dilution of 1: 200

Immunofluorescent analysis of paraformaldehyde-fixed human glioma using BRE (GB112384) at dilution of 1: 250

Immunofluorescent analysis of paraformaldehyde-fixed mouse brain using 

BRE (GB112384) at dilution of 1: 250

Immunofluorescent analysis of paraformaldehyde-fixed fetal mouse brain using BRE (GB112384) at dilution of 1: 250

Immunofluorescent analysis of paraformaldehyde-fixed mouse pancreas using BRE (GB112384) at dilution of 1: 250

Immunofluorescent analysis of paraformaldehyde-fixed rat placenta using 

BRE (GB112384) at dilution of 1: 250

 


 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.

 

NOTE: This product is intended for research only.

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