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GB11244 Anti -Glucose Transporter GLUT4 SLC2A4 Rabbit Polyclonal Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse GLUT4
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11244
  • Servicebio

Description

Product Information


Description

Glucose Transporter GLUT4

rabbit polyclonal

Protein full name

Solute carrier family 2, facilitated glucose transporter member 4

Synonyms

SLC2A4, GLUT4, solute carrier family 2 member 4

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse GLUT4

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell membrane, Endomembrane system,

Cytoplasm

Uniprot ID

P14142, P19357




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse, Rat

1: 500-1: 1500

skeletal muscle

IF

Mouse, Rat

1: 500-1: 1500

skeletal muscle




Background


At the cell surface, GLUT4 permits the facilitated diffusion of circulating glucose down its concentration gradient into muscle and fat cells. Once within cells, glucose is rapidly phosphorylated by glucokinase in the liver and hexokinase in other tissues to form glucose-6-phosphate, which then enters glycolysis or is polymerized into glycogen. Glucose-6-phosphate cannot diffuse back out of cells, which also serves to maintain the concentration gradient for glucose to passively enter cells.



Images



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Immunohistochemistry analysis of paraffin-embedded rat skeletal muscle using GLUT4 (GB11244) at dilution of 1: 800

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Immunohistochemistry analysis of paraffin-embedded mouse skeletal muscle using GLUT4 (GB11244) at dilution of 1: 1400




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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