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GB11253 Anti -Androgen Receptor AIS TFM SMAX1 SBMA Rabbit Polyclonal Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Androgen receptor
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11253
  • Servicebio

Description

Product Information


Description

Androgen receptor rabbit polyclonal

Protein full name

Androgen receptor

Synonyms

Dihydrotestosterone receptor, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM, Androgen receptor, AIS, AR, DHTR

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Androgen receptor

Isotype

IgG

Purity

Affinity purification

Subcellular location

Nucleus, Cytoplasm

Uniprot ID

P10275, P19091, P15207




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Human,

Mouse, Rat

1: 500-1: 1000

prostate, testis, seminal vesicle

IF

Human,

Mouse, Rat

1: 100-1: 500

prostate, testis, seminal vesicle




Background


Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.Isoform 3 and isoform 4 lack the C-terminal ligand-binding domain and may therefore constitutively activate the transcription of a specific set of genes independently of steroid hormones.



Images



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Immunohistochemistry analysis of paraffin-embedded human Prostate  using Androgen receptor (GB11253) at dilution of 1: 500

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Immunohistochemistry analysis of paraffin-embedded rat testis using Androgen receptor (GB11253) at dilution of 1: 500

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Immunohistochemistry analysis of paraffin-embedded mouse seminal vesicle using Androgen receptor (GB11253) at dilution of 1: 500




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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