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Anti -IL-22 Rabbit pAb for IHC IF primary antibody

Specification: 100uL
  • GB11259
  • Servicebio
  • Servicebio

Description

Product Information

 

 

Description

IL-22 rabbit polyclonal

Protein full name

Interleukin-22

Synonyms

IL22, IL-21, IL-22, IL-D110, IL-TIF, ILTIF, TIFIL-23, TIFa, zcyto18, interleukin 22

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse IL-22

Isotype IgG
Purity Affinity purification
Subcellular location

Secreted

Uniprot ID

Q9JJY9

 


 

Applications

 

 

Applications

IHC,IF

Species

Mouse

Dilution

1:400-1:800

Positive tissue

inflammatory lung

 


 

Background

 

 

IL-22 biological activity is initiated by binding to a cell-surface complex composed of IL-22R1 and IL-10R2receptor chains and further regulated by interactions with a soluble binding protein, IL-22BP, which shares sequence similarity with an extracellular region of IL-22R1 (sIL-22R1). IL-22 and IL-10 receptor chains play a role in cellular targeting and signal transduction to selectively initiate and regulate immune responses.IL-22 can contribute to immune disease through the stimulation of inflammatory responses, S100s and defensins. IL-22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-10.In some contexts, the pro-inflammatory versus tissue-protective functions of IL-22 are regulated by the often co-expressed cytokine IL-17A.

 


 

Images

 

 

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Immunohistochemistry analysis of paraffin-embedded mouse inflammatory lung using IL-22 (GB11259) at dilution of 1:400

   
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Immunohistochemistry analysis of paraffin-embedded mouse inflammatory lung using IL-22 (GB11259) at dilution of 1:800

 

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

 


 

NOTE: This product is intended for research only.

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