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Anti -PSD95 Rabbit pAb for WB IHC IF primary antibody

Specification: 100uL
  • GB11277
  • Servicebio
  • Servicebio

Description

Product Information


Description

PSD95 rabbit polyclonal

Protein full name

Disks large homolog 4

Synonyms

DLG4, PSD95, SAP-90, SAP90, Dlgh4, PSD-95, SAP90A, discs large homolog 4, discs large MAGUK scaffold protein 4

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse PSD95

Isotype

IgG

Predicted MW.

95 kDa

Observed MW.

95 kDa

Purity

Affinity purification

Subcellular location

Cell membrane, Cell junction

Uniprot ID

Q62108, P31016




Applications


applications

species

dilution

Positive tissue

WB

Mouse, Rat

1: 500-1: 1000

brain

IHC

Mouse, Rat

1: 100-1: 200

brain

IF

Mouse, Rat

1: 100-1: 200

brain




Background


Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B.

   



Images



GB11277.png

Western blot analysis of PSD95 (GB11277) at dilution of 1:750.

Line 1: mouse brain tissue lysate

Line 2:rat cerebral infarction tissue lysate

Line 3:rat brain tissue lysate

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Immunohistochemistry analysis of paraffin-embedded rat brain using PSD95 (GB11277) at dilution of 1:100

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Immunohistochemistry analysis of paraffin-embedded mouse brain using PSD95 (GB11277) at dilution of 1:100

Immunofluorescence analysis of paraffin-embedded rat brain using PSD95 (GB11277) at dilution of 1:200

Immunofluorescence analysis of paraffin-embedded mouse brain using PSD95 (GB11277) at dilution of 1:200




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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