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Anti -S6K1 Rabbit pAb Cell Cycle for IHC Research Antibody

Specification: 100uL
  • GB11298
  • Servicebio
  • Servicebio

Description

Product Information

Description

S6K1 rabbit polyclonal

Protein full name

Ribosomal protein S6 kinase beta-1

Synonyms

RPS6KB1, PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70 S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha, P70-S6 Kinase 1, ribosomal protein S6 kinase B1, p70S6K, p70S6 kinase

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse S6K1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cell junction, Mitochondrion, Mitochondrion outer membrane

Uniprot ID

P67999, Q8BSK8, P23443

 


 

Applications

 

 

Applications

IHC, IF

   
Species

Human, Mouse, Rat

   
Dilution

1: 500-1: 1000

   
Positive tissue

liver, brain

   

 


 

Background

 

Ribosomal protein S6 kinase beta-1 (S6K1), also known as p70S6 kinase (p70S6K, p70-S6K), is an enzyme(specifically, a protein kinase) that in humans is encoded by the RPS6KB1 gene. It is a serine/threonine kinase that acts downstream of PIP3 and phosphoinositide-dependent kinase-1 in the PI3 kinase pathway. As the name suggests, its target substrate is the S6 ribosomal protein. Phosphorylation of S6 induces protein synthesis at the ribosome.

 


 

Images

 

 

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Immunohistochemistry analysis of paraffin-embedded human liver using S6K1 (GB11298) at dilution of 1: 500

     
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Immunohistochemistry analysis of paraffin-embedded rat liver using S6K1 (GB11298) at dilution of 1: 500

     
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Immunohistochemistry analysis of paraffin-embedded rat brain using P70S6K1 (GB11298) at dilution of 1: 1000

     
image.png  

Immunohistochemistry analysis of paraffin-embedded mouse liver using P70S6K1 (GB11298) at dilution of 1: 500

     
image.png  

Immunohistochemistry analysis of paraffin-embedded mouse brain using P70S6K1 (GB11298) at dilution of 1: 1000

 


 

Storage

 

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.

 


 

NOTE: This product is intended for research only.

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