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Anti -S6K1 Rabbit pAb Immunohistochemistry primary antibody Immunofluorescence antibody

Specification: 100uL
  • GB11298A
  • Servicebio
  • Servicebio

Description

Product Information


Description

S6K1 rabbit polyclonal

Protein full name

Ribosomal protein S6 kinase beta-1

Synonyms

S6K-beta-1, S6K1, P70S6K1, S6K, Ribosomal protein S6 kinase I, P70 S6 kinase alpha, Rps6kb1, 70 kDa ribosomal protein S6 kinase 1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse S6K1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm

Uniprot ID

P67999, Q8BSK8, P23443




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Human, Mouse, Rat

1: 500-1: 1000

liver, brain

IF

Human, Mouse, Rat

1: 500-1: 1000

liver, brain




Background


Ribosomal protein S6 kinase beta-1 (S6K1), also known as p70S6 kinase (p70S6K, p70-S6K), is an enzyme(specifically, a protein kinase) that in humans is encoded by the RPS6KB1 gene. It is a serine/threonine kinase that acts downstream of PIP3 and phosphoinositide-dependent kinase-1 in the PI3 kinase pathway. As the name suggests, its target substrate is the S6 ribosomal protein. Phosphorylation of S6 induces protein synthesis at the ribosome.





Images

Immunohistochemistry analysis of paraffin-embedded human liver using S6K1 (GB11298A) at dilution of 1: 500

Immunohistochemistry analysis of paraffin-embedded rat liver using S6K1 (GB11298A) at dilution of 1: 500

Immunohistochemistry analysis of paraffin-embedded rat brain using P70S6K1 (GB11298A) at dilution of 1: 1000

Immunohistochemistry analysis of paraffin-embedded mouse liver using P70S6K1 (GB11298A) at dilution of 1: 500

Immunohistochemistry analysis of paraffin-embedded mouse brain using P70S6K1 (GB11298A) at dilution of 1: 1000




Storage


Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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