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Anti -GilZ / TilZ Rabbit PAb for IHC IF Primary Antibody

Specification: 100uL
  • GB11303
  • Servicebio
  • Servicebio

Description

Product Information


Description

GILZ rabbit polyclonal

Protein full name

TSC22 domain family protein 3

Synonyms

TSC22D3, DIP, DSIPI, GILZ, TSC-22R, hDIP, TSC22 domain family member 3

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse GILZ

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus

Uniprot ID

Q9Z2S7, Q9EQZ1




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Mouse, Rat

1: 800

testis, brain, lung,

kidney, ovary

IF

Mouse, Rat

1: 800

testis, brain, lung,

kidney, ovary




Background


Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities (By similarity). Isoform 1 and isoform 4 inhibit myogenic differentiation and mediate anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcriptional activity resulting in reduced expression of MYOG.



Images



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Immunohistochemistry analysis of paraffin-embedded rat testis using GILZ (GB11303) at dilution of 1: 800

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Immunohistochemistry analysis of paraffin-embedded rat brain using GILZ (GB11303) at dilution of 1: 800

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Immunohistochemistry analysis of paraffin-embedded mouse lung using GILZ (GB11303) at dilution of 1: 800

Immunohistochemistry analysis of paraffin-embedded mouse testis using GILZ(GB11303) at dilution of 1: 800

Immunohistochemistry analysis of paraffin-embedded mouse ovary using GILZ(GB11303) at dilution of 1: 800

Immunohistochemistry analysis of paraffin-embedded mouse kidney using GILZ(GB11303) at dilution of 1: 800




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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