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Anti -MEK1 Rabbit PAb for IHC IF Primary Antibody

Specification: 100uL
  • GB11304
  • Servicebio
  • Servicebio

Description

Product Information


Description

MEK1 rabbit polyclonal

Protein full name

Dual specificity mitogen-activated protein kinase kinase 1

Synonyms

MAP2K1, CFC3, MAPKK1, MEK1, MKK1, PRKMK1, mitogen activated protein kinase kinase 1, ERK activator kinase 1, MAP kinase kinase 1

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse MEK1

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm , Nucleus, Membrane

Uniprot ID

Q02750, Q01986, P31938




Applications


applications

species

dilution

Positive tissue

IHC

Human, Mouse, Rat

1: 100

colon, breast cancer, liver, ovary, testis, spleen

IF

Human, Mouse, Rat

1: 100

colon, breast cancer, liver, ovary, testis, spleen




Background


The protein is a member of the dual-specificity protein kinase family that acts as amitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon activation by a wide variety of extra- and intracellular signals. As an essential component of the MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.




Images



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Immunohistochemistry analysis of paraffin-embedded human colon using MEK1 (GB11304) at dilution of 1:100

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Immunohistochemistry analysis of paraffin-embedded human breast cancer using MEK1 (GB11304) at dilution of 1:100

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Immunohistochemistry analysis of paraffin-embedded rat liver using MEK1 (GB11304) at dilution of 1:100

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Immunohistochemistry analysis of paraffin-embedded rat ovary using MEK1 (GB11304) at dilution of 1:100

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Immunohistochemistry analysis of paraffin-embedded mouse testis using MEK1 (GB11304) at dilution of 1:100

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Immunohistochemistry analysis of paraffin-embedded mouse spleen using MEK1 (GB11304) at dilution of 1:100




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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