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Anti -IKB beta Rabbit pAb for Immunohistochemical immunofluorescence primary antibody

Specification:100uL
  • GB11306
  • Servicebio
  • Servicebio

Description

Product Information


Description

IKB beta rabbit polyclonal

Protein full name

NF-kappa-B inhibitor beta

Synonyms

NFKBIB, IKBB, IkB-beta, IkappaBbeta, TRIP9, NFKB inhibitor beta

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse IKBβ

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytoplasm, Nucleus

Uniprot ID

Q60778, Q9JIA3, Q15653




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Human, Mouse, Rat

1: 300

lung, kidney, colon,

liver, testis

IF

Human, Mouse, Rat

1: 300

lung, kidney, colon,

liver, testis




Background


Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.




Images



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Immunohistochemistry analysis of paraffin-embedded human lung cancer  using IKBβ (GB11306) at dilution of 1: 300

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Immunohistochemistry analysis of paraffin-embedded human colon using IKBβ (GB11306) at dilution of 1: 300

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Immunohistochemistry analysis of paraffin-embedded mouse lung using IKBβ (GB11306) at dilution of 1: 300


Immunohistochemistry analysis of paraffin-embedded mouse kidney using IKBβ (GB11306) at dilution of 1: 300

Immunohistochemistry analysis of paraffin-embedded rat liver using IKBβ (GB11306) at dilution of 1: 300

Immunohistochemistry analysis of paraffin-embedded rat testis using IKBβ (GB11306) at dilution of 1: 300




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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