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Anti -Aquaporin 4 Rabbit PAb for Rat IHC IF Primary Antibody

Specification: 100uL
  • GB11311-1
  • Servicebio
  • Servicebio

Description

Product Information


Description

Aquaporin 4 rabbit polyclonal

Protein full name

Aquaporin-4

Synonyms

AQP4, aquaporin 4, HMIWC2, MIWC, WCH4

Immunogen

KLH conjugated Synthetic peptide corresponding to Rat Aquaporin 4

Isotype

IgG

Purity

Affinity purification

Subcellular location

Membrane

Uniprot ID

P47863




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Rat

1: 500-1: 1000

brain, hippocampus

IF

Rat

1: 500-1: 1000

brain, hippocampus




Background


Aquaporin-4, also known as AQP4, is a water channel protein .Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system. It is expressed predominantly in the ependymal cell lining the aqueductal system and over the space of the brain in contact with the subarachnoid space, as cerebrospinal fluid fills these structures it may facilitate water balance between brain parenchyma and the fluid compartment. In the plasma membranes of the neurons of the paraventricular and supraoptic nuclei, it may mediate rapid changes in cell volume in response to local shifts in extracellular osmolarity.




Images



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Immunohistochemistry analysis of paraffin-embedded rat hippocampus using Aquaporin 4 (GB11311-1) at dilution of 1: 1000

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Immunohistochemistry analysis of paraffin-embedded rat brain using

Aquaporin 4 (GB11311-1) at dilution of 1: 1000




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

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