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Anti -CD163 Rabbit pAb Polyclonal antibody for WB

Specification: 100uL
  • GB11340
  • Servicebio
  • Servicebio

Description

Product Information


Description

CD163 rabbit polyclonal

Protein full name

Scavenger receptor cysteine-rich type 1 protein M130

Synonyms

CD163, M130, MM130, SCARI1, CD163 molecule

Immunogen

Recombinant protein corresponding to Mouse CD163

Isotype

IgG

Purity

Affinity purification

Predicted MW.

125 kDa

Observed MW.

145 kDa

Uniprot ID

Q2VLH6, Q86VB7




Applications


applications

species

dilution

Positive tissue

WB

Human, Mouse, Rat

1: 1200-1: 1500

spleen, lung, lymph nodes




Background


Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1 (By similarity).

   



Images



GB11340.png

Western blot analysis of CD163 (GB11340) at dilution of 1:1200.

Lane 1:MH-S cell lysate

Lane 2:Raw264.7 cell lysate

Lane 3:Mouse spleen tissue lysate

Lane 4:Mouse lung tissue lysate

Lane 5:Mouse lymph nodes tissue lysate

Lane 6:Rat lung tissue lysate

image.png

Western blot analysis of CD163 (GB11340) at dilution of 1:1200.

Lane 1:SH-SY5Y cell lysate

Lane 2:THP-1 cell lysate

Lane 3:Raw264.7 cell lysate




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE: This product is intended for research only.

downLoadImgSlice 13Laboratory(1)Slice 10Slice 12

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