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GB11368 Anti -IRF3 IIAE7 Rabbit Polyclonal Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse IRF3
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11368
  • Servicebio

Description

Product Information


Description

IRF3 rabbit polyclonal

Protein full name

Interferon regulatory factor 3

Synonyms

IRF3, entrez:3661, IIAE7, interferon regulatory factor 3

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse IRF3

Isotype

IgG

Purity

Affinity purification

Predicted MW.

47 kDa

Observed MW.

50 kDa

Uniprot ID

P70671, Q14653




Applications


applications

species

dilution

Positive tissue

WB

Human, Mouse, Rat

1: 500-1: 1000

brain, spinal marrow




Background


IRF3 is a member of the interferon regulatory transcription factor (IRF) family. IRF3 was originally discovered as a homolog of IRF1 and IRF2. IRF3 has been further characterized and shown to contain several functional domains including a nuclear export signal, a DNA-binding domain, a C-terminal IRF association domain and several regulatory phosphorylation sites. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP.This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.




Images



GB11368.png

Western blot analysis of IRF3 (GB11368) at dilution of 1:600.

Lane 1: Hela cell lysate

Lane 2: MCF7 cell lysate

Lane 3: Jurkat cell lysate

Lane 4: Mouse kidney tissue lysate

Lane 5: Mouse spinal marrow tissue lysate

Lane 6: Mouse brain tissue lysate

Lane 7: Rat kidney tissue lysate

Lane 8: Rat spinal marrow tissue lysate

Lane 9: Rat brain tissue lysate




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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