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GB11377 Anti -UCP2 Rabbit pAb Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse UCP2
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11377
  • Servicebio

Description

Product Information


Description

UCP2 rabbit polyclonal

Protein full name

Mitochondrial uncoupling protein 2

Synonyms

UCP2, BMIQ4, SLC25A8, UCPH, uncoupling protein 2

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse UCP2

Isotype

IgG

Purity

Affinity purification

Subcellular location

Mitochondrion inner membrane

Uniprot ID

P70406, P55851, P56500




Applications


applications

species

dilution

Positive tissue

IHC

Human, Mouse, Rat

1: 200-1: 600

lymphoma, spleen,

lung

IF

Human, Mouse, Rat

1: 200-1: 600

lymphoma, spleen,

lung




Background


Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle.




Images



image.png

Immunohistochemistry analysis of paraffin-embedded human lymphoma using UCP2(GB11377) at dilution of 1:300

image.png

Immunohistochemistry analysis of paraffin-embedded mouse spleen using UCP2(GB11377) at dilution of 1:300

image.png

Immunohistochemistry analysis of paraffin-embedded rat lung using UCP2(GB11377) at dilution of 1:300




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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