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GB11378 Anti -BAG2 Rabbit pAb Antibody

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Bag2
Isotype: IgG
Purity: Affinity purification
ul:
  • GB11378
  • Servicebio

Description

Product Information


Description

BAG2 rabbit polyclonal

Protein full name

BAG family molecular chaperone regulator 2

Synonyms

BAG2, BAG-2, dJ417I1.2, BCL2 associated athanogene 2, Bag2

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Bag2

Isotype

IgG

Purity

Affinity purification

Subcellular location

Cytosol

Uniprot ID

Q91YN9




Applications


Applications

Species

Dilution

Positive Tissue

IHC

Rat

1: 500-1: 1000

spleen, lymph node


IF

Rat

1: 500-1: 1000

spleen, lymph node





Background


BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.



Images



image.png

Immunohistochemistry analysis of paraffin-embedded rat lymph node using Bag2 (GB11378) at dilution of 1: 1000

image.png

Immunohistochemistry analysis of paraffin-embedded rat spleen using Bag2 (GB11378) at dilution of 1: 1000




Storage



Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.




NOTE:

1.This product is intended for research only.

2.This product is recommended to dilute with the Primary Antibody Dilution Buffer (G2025).

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